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Review

Human ABC transporter ABCG2/BCRP expression in chemoresistance: basic and clinical perspectives for molecular cancer therapeutics

, &
Pages 53-64 | Published online: 05 Feb 2014

Figures & data

Figure 1 Schematic diagram of ABCG2/BCRP protein and its amino acid variations. Amino acid variations by single-nucleotide polymorphisms are marked with stars. Transmembrane domains are shown as cylinders.

Abbreviations: ABC, adenine-triphosphate-binding cassette; BCRP, breast cancer resistance protein.
Figure 1 Schematic diagram of ABCG2/BCRP protein and its amino acid variations. Amino acid variations by single-nucleotide polymorphisms are marked with stars. Transmembrane domains are shown as cylinders.

Table 1 Interactions between tyrosine kinase inhibitors and ABCG2/BCRP

Table 2 Single-nucleotide polymorphisms of the ABCG2/BCRP gene