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Management Strategies of Patients with Neuromyelitis Optica Spectrum Disorder During the COVID-19 Pandemic Era

Sherif M HamdyNeurology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

Maged Abdel-NaseerNeurology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

https://orcid.org/0000-0002-2053-980X

Hatem S ShehataNeurology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

https://orcid.org/0000-0002-4865-1457

Nevin M ShalabyNeurology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

Amr HassanNeurology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

https://orcid.org/0000-0001-7374-7074

Alaa ElmaznyNeurology Department, Faculty of Medicine, Cairo University, Cairo, EgyptCorrespondence[email protected]

https://orcid.org/0000-0002-3556-3749

Ehab ShakerNeurology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

Mona A F NadaNeurology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

https://orcid.org/0000-0002-8969-8825

Sandra M AhmedNeurology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

Mohamed I HegazyNeurology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

https://orcid.org/0000-0001-5012-3998

Husam S MouradNeurology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

https://orcid.org/0000-0002-1994-3186

Ahmed AbdelalimNeurology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

https://orcid.org/0000-0001-6445-5539

Rehab MagdyNeurology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

Alshimaa S OthmanNeurology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

https://orcid.org/0000-0003-0976-9011

Doaa A MekkawyNeurology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

Nirmeen A KishkNeurology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

https://orcid.org/0000-0003-4410-7814

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Figure 1 Management of a relapse in NMOSD patients during COVID-19 pandemic.^Citation32

*After improvement continue on oral steroids for 3-6 months and consider initiation of disease-modifying therapies in newly diagnosed patients.

Abbreviations: CBC, complete blood count; COVID-19, coronavirus disease 2019; CRP, C reactive protein; CT, computed tomography; IVIG, intravenous immunoglobulins; IVMP, intravenous methylprednisolone; NMOSD, neuromyelitis optica spectrum disorder; PLEX, plasma exchange.

Figure 1 Management of a relapse in NMOSD patients during COVID-19 pandemic.Citation32*After improvement continue on oral steroids for 3-6 months and consider initiation of disease-modifying therapies in newly diagnosed patients.Abbreviations: CBC, complete blood count; COVID-19, coronavirus disease 2019; CRP, C reactive protein; CT, computed tomography; IVIG, intravenous immunoglobulins; IVMP, intravenous methylprednisolone; NMOSD, neuromyelitis optica spectrum disorder; PLEX, plasma exchange.

Figure 2 Algorithm for initiation and maintenance of DMTs in NMOSD patients during the COVID-19 pandemic.

Abbreviations: ABs, antibodies; COVID-19, coronavirus disease 2019; CTX, cyclophosphamide; DMT, disease modifying therapy; IVIG, intravenous immunoglobulins; MMF, mycophenolate mofetil; MTX, methotrexate; NMOSD, neuromyelitis optica spectrum disorder.

Management Strategies of Patients with Neuromyelitis Optica Spectrum Disorder During the COVID-19 Pandemic Era

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Management Strategies of Patients with Neuromyelitis Optica Spectrum Disorder During the COVID-19 Pandemic Era

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