Aberrant S-nitrosylation of MEF2 (forming SNO-MEF2) controls neuronal differentiation and survival in context- and disease-dependent manners [Citation8,Citation9]. The SNO-MEF2C/PGC1α pathway is involved in death of A9 dopaminergic neurons in Parkinson’s disease [Citation8]. The SNO-MEF2C/Bcl-xL pathway contributes to cerebrocortical neuron death in stroke [Citation9]. The SNO-MEF2A/TLX cascade negatively regulates adult neurogenesis in Alzheimer’s disease [Citation9].
![Figure 1. Context- and disease-dependent pathways regulated by SNO-MEF2.Aberrant S-nitrosylation of MEF2 (forming SNO-MEF2) controls neuronal differentiation and survival in context- and disease-dependent manners [Citation8,Citation9]. The SNO-MEF2C/PGC1α pathway is involved in death of A9 dopaminergic neurons in Parkinson’s disease [Citation8]. The SNO-MEF2C/Bcl-xL pathway contributes to cerebrocortical neuron death in stroke [Citation9]. The SNO-MEF2A/TLX cascade negatively regulates adult neurogenesis in Alzheimer’s disease [Citation9].](/cms/asset/42588751-6c76-46ce-b940-ef8584acaf86/ifnl_a_12329546_f0001.jpg)
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
