Craving is associated with amygdala volumes in adolescent marijuana users during abstinence

Figures & data

Table 1. Characteristics of abstinent adolescent marijuana users (n = 22).

	M (SD)
Age	17.8 (0.9)
% Female	23%
% Caucasian	55%
Pubertal development scale score	3.5 (0.4)
Parent annual salary	109.3 (93.8)
WASI Vocabulary T-score	56.1 (8.0)
Beck Depression Inventory Score	3.1 (2.6)
Hamilton Anxiety Rating Scale	3.7 (5.5)
Lifetime alcohol use episodes	220.5 (178.6)
Years of MJ use	2.6 (1.6)
Age first used MJ regularly (weekly)	14.5 (3.6)
Lifetime MJ use episodes	436.9 (361.0)
MJ craving score (1 question)	16.3 (23.2)
Mood score (5 questions)	44.4 (45.3)
Sleep score (5 questions)	82.4 (57.6)
Appetite score (1 question)	8.9 (12.9)
Somatic score (5 questions)	21.7 (23.4)
Intracranial volume (in cc^3)	1574.6 (129.0)
Left amygdala volume (in cc^3)	2.0 (0.3)
Right amygdala volume (in cc^3)	2.3 (0.4)

WASI, Wechsler Abbreviated Scale of Intelligence; MJ, marijuana.

Figure 1. Scatterplot of craving symptom scores predicting right and left amygdala to intracranial volume ratios in 22 abstinent adolescent marijuana users.

Figure 2. Average craving rating for chronic marijuana users across nine time-points collected over 28 days of abstinence.