Clinical impact of potentially inappropriate medications during hospitalization of acutely ill older patients with multimorbidity

Hege KerstenDepartment of Geriatric Medicine, Vestfold Hospital Trust, Tønsberg, Norway, ;Norwegian National Advisory Unit on Ageing and Health, Tønsberg, Norway, ;Geriatric Psychiatry Research Network, Telemark Hospital Trust and Vestfold Hospital Trust, Norway, Correspondence[email protected]

Lara T HvidstenDepartment of Geriatric Medicine, Vestfold Hospital Trust, Tønsberg, Norway, ;Norwegian National Advisory Unit on Ageing and Health, Tønsberg, Norway,

Gløer GløersenThe Hospital Pharmacies, Vestfold, South-Eastern Norway Regional Health Authority, Norway,

Torgeir Bruun WyllerInstitute of Clinical Medicine, University of Oslo, Oslo, Norway, and ;Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway

Marte Sofie Wang-HansenDepartment of Geriatric Medicine, Vestfold Hospital Trust, Tønsberg, Norway, ;Institute of Clinical Medicine, University of Oslo, Oslo, Norway, and

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Figure 1. Reasons for acute admission to Vestfold Hospital Trust; N = 232, X-axis = n/N. VTE = venous thromboembolism.

Table 1. Study sample (n = 232) characteristics (n = valid cases for each characteristic).

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Table 2. Prevalence of potentially inappropriate medications (PIMs) at acute hospital admission and dischargeTable Footnote¹.

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Table 3. Frequencies of drug changes in geriatric ward versus other medical wards.

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Figure 2. Hand-grip strength measured by dynamometer for non-users (0) and users (1) of ≥ 3 psychotropic drugs or opioids (criterion 9).

Table 4. Analyses of variance (ANOVA) comparing mean differences in clinical outcome measures between patients with 0, 1, and ≥ 2 PIMs at hospital admission.

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Appendix 1. Fifty-three criteria for potentially inappropriate medications in older adults based on NORGEP and Beers’ 2012, and categorized into nine subgroups.

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Clinical impact of potentially inappropriate medications during hospitalization of acutely ill older patients with multimorbidity

Table 1. Study sample (n = 232) characteristics (n = valid cases for each characteristic).

Table 2. Prevalence of potentially inappropriate medications (PIMs) at acute hospital admission and dischargeTable Footnote¹.

Table 3. Frequencies of drug changes in geriatric ward versus other medical wards.

Table 4. Analyses of variance (ANOVA) comparing mean differences in clinical outcome measures between patients with 0, 1, and ≥ 2 PIMs at hospital admission.

Appendix 1. Fifty-three criteria for potentially inappropriate medications in older adults based on NORGEP and Beers’ 2012, and categorized into nine subgroups.

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Clinical impact of potentially inappropriate medications during hospitalization of acutely ill older patients with multimorbidity

Figures & data

Table 1. Study sample (n = 232) characteristics (n = valid cases for each characteristic).

Table 2. Prevalence of potentially inappropriate medications (PIMs) at acute hospital admission and dischargeTable Footnote1.

Table 3. Frequencies of drug changes in geriatric ward versus other medical wards.

Table 4. Analyses of variance (ANOVA) comparing mean differences in clinical outcome measures between patients with 0, 1, and ≥ 2 PIMs at hospital admission.

Appendix 1. Fifty-three criteria for potentially inappropriate medications in older adults based on NORGEP and Beers’ 2012, and categorized into nine subgroups.

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Table 2. Prevalence of potentially inappropriate medications (PIMs) at acute hospital admission and dischargeTable Footnote¹.