Figures & data
Figure 1. Syntheses of compounds; (A) for 1, and (B) for 2.
Table 1. Crystal data and structure refinement details for compounds 1 and 2.
Figure 2. The molecular structure and atomic labeling scheme of 1. Displacement ellipsoids are drawn at the 40% probability level.
Figure 3. The molecular structure and atomic labeling scheme of 2. Displacement ellipsoids are drawn at the 40% probability level.
Figure 4. SDS-PAGE analyses of CA isoenzymes: (a) Standard hCA I, (b) isolated hCA I, (c) Standard hCA II and (d) isolated hCA II.
Figure 5. Ki graph obtained from in vitro studies for compound 1 on hCA II.
Table 2. Selected bond distances (Å) and angles (°) for compounds 1 and 2.
Figure 6. FTIR spectra of en, Hsba, amp, compounds 1 and 2 (KBr).
Figure 7. The TG-DTG and DTA curves of 1.
Figure 8. The TG-DTG and DTA curves of 2.
Table 3. Optical properties of compounds 1 and 2, and the free ligands amp and Hsba, in water and DMSO.
Figure 9. UV-Vis spectra of en, Hsba, amp, compounds 1 and 2; (A) in water, (B) in DMSO.
Table 4. IC50 and Ki values of hCA-I and hCA-II isoenzyme hydratase and esterase activities after inhibition experiments.