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Research Article

Anti-inflammatory phenolics isolated from Juniperus rigida leaves and twigs in lipopolysaccharide-stimulated RAW264.7 macrophage cells

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Pages 875-879 | Received 08 Aug 2011, Accepted 14 Sep 2011, Published online: 03 Nov 2011

Figures & data

Figure 1.  Inhibitory effects on NO production and cytotoxicity of total extract and each fraction (A and B), and compounds 113 (C and D) isolated from J. rigida leaves and twigs in LPS-stimulated RAW264.7 cells. The RAW264.7 cells were pretreated with each sample to be tested for 1 h before exposure to LPS for 24 h. The concentration of nitrite in culture medium was measured by Griess reaction and sodium nitrite was used as a standard. The values shown are mean ± SD of three independent experiments. The results differ significantly from LPS-only treated; *p < 0.01, **p < 0.001.

Figure 1.  Inhibitory effects on NO production and cytotoxicity of total extract and each fraction (A and B), and compounds 1−13 (C and D) isolated from J. rigida leaves and twigs in LPS-stimulated RAW264.7 cells. The RAW264.7 cells were pretreated with each sample to be tested for 1 h before exposure to LPS for 24 h. The concentration of nitrite in culture medium was measured by Griess reaction and sodium nitrite was used as a standard. The values shown are mean ± SD of three independent experiments. The results differ significantly from LPS-only treated; *p < 0.01, **p < 0.001.

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