Views

CrossRef citations to date

Altmetric

Research Article

Antitumor activity of amidino-substituted benzimidazole and benzimidazo[1,2-a]quinoline derivatives tested in 2D and 3D cell culture systems

Karmen BrajšaPharmacology in Vitro, Zagreb, Croatia, Correspondence[email protected]

Ines VujasinovićChemistry, Fidelta D.O.O., Zagreb, Croatia, and

Dubravko JelićPharmacology in Vitro, Zagreb, Croatia,

Marija TrzunPharmacology in Vitro, Zagreb, Croatia,

Ivo ZlatarPharmacology in Vitro, Zagreb, Croatia,

Grace Karminski-ZamolaDepartment of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Zagreb, Croatia

Marijana HranjecDepartment of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Zagreb, CroatiaCorrespondence[email protected]

show all

Figures & data

Figure 1. Tested compounds.

Scheme 1. Synthesis of compounds 3a–3i, 4a–4d and 5a–5c.

Scheme 2. Synthesis of compounds 7 and 8.

Scheme 3. Synthesis of compounds 10a–10d and 11a–11b.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Antitumor activity of amidino-substituted benzimidazole and benzimidazo[1,2-a]quinoline derivatives tested in 2D and 3D cell culture systems

Table 1. IC₅₀ of 22 compounds on 2D assay.

Table 2. IC₅₀ of standard drugs on 2D and 3D assay.

Table 3. Comparison of IC₅₀ of selected NCE on 3D and 2D assay.

Information for

Open access

Opportunities

Help and information

Your download is now in progress and you may close this window

Login or register to access this feature

Antitumor activity of amidino-substituted benzimidazole and benzimidazo[1,2-a]quinoline derivatives tested in 2D and 3D cell culture systems

Figures & data

Table 1. IC50 of 22 compounds on 2D assay.

Table 2. IC50 of standard drugs on 2D and 3D assay.

Table 3. Comparison of IC50 of selected NCE on 3D and 2D assay.

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Table 1. IC₅₀ of 22 compounds on 2D assay.

Table 2. IC₅₀ of standard drugs on 2D and 3D assay.

Table 3. Comparison of IC₅₀ of selected NCE on 3D and 2D assay.