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Review

Probiotics: Current Landscape and Future Horizons

, , , & ORCID Icon
Article: FSO391 | Received 11 Jan 2019, Accepted 20 Mar 2019, Published online: 03 May 2019

Figures & data

Figure 1. A diagrammatic overview of the positive and negative influence of gut bacteria represented across a wide-range of health and disease conditions.

Figure 1. A diagrammatic overview of the positive and negative influence of gut bacteria represented across a wide-range of health and disease conditions.

Figure 2. Annual (top) and cumulative (bottom) trend of published research manuscripts indexed on MEDLINE/PubMed matching the terms ‘probiotics’ AND (‘health’ OR ‘disease’) [data refer to search conducted on 27 November 2018].

Figure 2. Annual (top) and cumulative (bottom) trend of published research manuscripts indexed on MEDLINE/PubMed matching the terms ‘probiotics’ AND (‘health’ OR ‘disease’) [data refer to search conducted on 27 November 2018].

Figure 3. Overview of multi-omics technologies and associated analytical techniques.

GC: Gas chromatography; HPLC: High-performance liquid chromatography; LC-MS: Liquid chromatography–mass spectrometry; MALDI: Matrix-assisted laser desorption ionization; MS: Mass spectrometry; NGS: Next-generation sequencing; NMR = nuclear magnetic resonance.

Figure 3. Overview of multi-omics technologies and associated analytical techniques.GC: Gas chromatography; HPLC: High-performance liquid chromatography; LC-MS: Liquid chromatography–mass spectrometry; MALDI: Matrix-assisted laser desorption ionization; MS: Mass spectrometry; NGS: Next-generation sequencing; NMR = nuclear magnetic resonance.

Figure 4. A schematic drawing to demonstrate gut bacterial metabolism of dietary components choline and L-carnitine into TMA which is subsequently converted to TMAO by liver flavin-containing monooxygenases (e.g., FMO3).

TMA: Trimethylamine; TMAO: Trimethylamine N-oxide.

Figure 4. A schematic drawing to demonstrate gut bacterial metabolism of dietary components choline and L-carnitine into TMA which is subsequently converted to TMAO by liver flavin-containing monooxygenases (e.g., FMO3).TMA: Trimethylamine; TMAO: Trimethylamine N-oxide.