Figures & data
Figure 1. Heat stress memory is regulated by the HSFA2 cascade and the miR156-SPL module. Heat stress induces expression of HSFA2 which in turn activates HSA32 and additional target genes that maintain acquired thermotolerance (HS memory). This also requires ROF1 activity. Maintenance of acquired thermotolerance is also promoted by increased repression of SPL2 and other targets through miR156. Biogenesis of miR156 requires DCL1 and repression of SPL2 and other target mRNAs requires AGO1. The miR156-SPL module also regulates leaf initiation rates and the transition to flowering. Thus, its dual role in heat stress memory and the regulation of development may serve to integrate development with environmental stress.
