11,457
Views
97
CrossRef citations to date
0
Altmetric
REVIEWS

What is a pathogen? Toward a process view of host-parasite interactions

&
Pages 775-785 | Received 31 Jan 2014, Accepted 27 Aug 2014, Published online: 20 Jan 2015

Figures & data

Fig. 1. Spatial schema representing how the virulence of an infection arises (A) and how a biological association moves from virulence to pathogenicity (B). Note that in (A) the genotype only partly determines the phenotype and that the environment includes many factors (e.g., multiple infections). In (B), one needs to set a threshold value in order to decide when a parasite is virulent enough to be considered a pathogen. The rectangle illustrates the uncertainty in defining such a value.

Fig. 1. Spatial schema representing how the virulence of an infection arises (A) and how a biological association moves from virulence to pathogenicity (B). Note that in (A) the genotype only partly determines the phenotype and that the environment includes many factors (e.g., multiple infections). In (B), one needs to set a threshold value in order to decide when a parasite is virulent enough to be considered a pathogen. The rectangle illustrates the uncertainty in defining such a value.