Artificial DNA and surface plasmon resonance

Figures & data

Figure 1. Schematic description of the protocol used to detect adenosine by using an aptamer-based gold nanoparticle enhanced SPR protocol. Reproduced with permission by the American Chemical Society.⁴¹

Figure 2. Pictorial description of the nanoparticle-enhanced SPRI strategy used to detect the normal, heterozygous and homozygous genomic DNAs. PNA-N and PNA-M specifically recognize the normal β-globin and the mutated β°39-globin genomic sequences respectively. Reproduced with permission by the American Chemical Society.⁸⁹

Wang J, Zhou HS. Aptamer-based Au nanoparticles-enhanced surface plasmon resonance detection of small molecules. Anal Chem 2008; 80:7174 - 8; http://dx.doi.org/10.1021/ac801281c; PMID: 18707133

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D’Agata R, Breveglieri G, Zanoli LM, Borgatti M, Spoto G, Gambari R. Direct detection of point mutations in nonamplified human genomic DNA. Anal Chem 2011; 83:8711 - 7; http://dx.doi.org/10.1021/ac2021932; PMID: 21978174

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