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Autophagy Volume 10, 2014 - Issue 11
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Editor's Corner

Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers

Guillermo MariñoEquipe 11 labellisée par la Ligue Nationale contre le cancer; INSERM U1138; Center de Recherche des Cordeliers; Paris, France;Université Paris Descartes; Sorbonne Paris Cité; Paris, France
,
Federico PietrocolaEquipe 11 labellisée par la Ligue Nationale contre le cancer; INSERM U1138; Center de Recherche des Cordeliers; Paris, France;Université de Paris Sud; Villejuif, France
,
Frank MadeoInstitute of Molecular Biosciences; University of Graz; Graz, AustriaCorrespondence[email protected] [email protected]
&
Guido KroemerEquipe 11 labellisée par la Ligue Nationale contre le cancer; INSERM U1138; Center de Recherche des Cordeliers; Paris, France;Université Paris Descartes; Sorbonne Paris Cité; Paris, France;Metabolomics and Molecular Cell Biology Platforms; Gustave Roussy; Villejuif, France;Pôle de Biologie; Hôpital Européen Georges Pompidou; AP-HP; Paris, FranceCorrespondence[email protected] [email protected]
Pages 1879-1882 | Received 23 Jul 2014, Accepted 27 Sep 2014, Published online: 18 Dec 2014

Figures & data

Figure 1. Caloric restriction and its pharmacological mimetics. (A) General outline of the mechanisms of health improvement by caloric restriction (CR). (B) Molecular mechanism of autophagy induction by CR. (C) Mechanism of action of caloric restriction mimetics (CRMs). (D) Hypothetical mechanisms of anti-aging effects of CR and CRMs.

Figure 1. Caloric restriction and its pharmacological mimetics. (A) General outline of the mechanisms of health improvement by caloric restriction (CR). (B) Molecular mechanism of autophagy induction by CR. (C) Mechanism of action of caloric restriction mimetics (CRMs). (D) Hypothetical mechanisms of anti-aging effects of CR and CRMs.

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