Autophagy, Volume 10, Issue 11 (2014)

Browse this journal
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Autophagy, Volume 10, Issue 11 (2014)

See all volumes and issues
Vol 20, 2024 Vol 19, 2023 Vol 18, 2022 Vol 17, 2021 Vol 16, 2020 Vol 15, 2019 Vol 14, 2018 Vol 13, 2017 Vol 12, 2016 Vol 11, 2015 Volume 10, 2014 Vol 9, 2013 Vol 8, 2012 Vol 7, 2011 Vol 6, 2010 Vol 5, 2009 Vol 4, 2008 Vol 3, 2007 Vol 2, 2006 Vol 1, 2005
Download citations Download PDFs Download issue

Editor's Corner

Article
Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers
Guillermo Mariño, Federico Pietrocola, Frank Madeo & Guido Kroemer
Pages: 1879-1882
Published online: 18 Dec 2014
AbstractforCaloric restriction mimetics: natural/physiological pharmacological autophagy inducers | Full Text | References | PDF (269.2 KB)
  • 7929 Views
  • 83 CrossRef citations
  • 0Altmetric
Open Access

Brief Reports

Article
Autophagy is not required to sustain exercise and PRKAA1/AMPK activity but is important to prevent mitochondrial damage during physical activity
Francesca Lo Verso, Silvia Carnio, Anna Vainshtein & Marco Sandri
Pages: 1883-1894
Published online: 30 Oct 2014
AbstractforAutophagy is not required to sustain exercise and PRKAA1/AMPK activity but is important to prevent mitochondrial damage during physical activity | Full Text | References | PDF (1.3 MB) | Supplemental
  • 4683 Views
  • 106 CrossRef citations
  • 0Altmetric
Open Access
Article
Vacuolin-1 potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A
Yingying Lu, Shichen Dong, Baixia Hao, Chang Li, Kaiyuan Zhu, Wenjing Guo, Qian Wang, King-Ho Cheung, Connie WM Wong, Wu-Tian Wu, Huss Markus & Jianbo Yue
Pages: 1895-1905
Published online: 30 Oct 2014
AbstractforVacuolin-1 potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A | Full Text | References | PDF (886.6 KB) | Supplemental
  • 6598 Views
  • 86 CrossRef citations
  • 0Altmetric
Open Access

Basic Research Papers

Article
Choline dehydrogenase interacts with SQSTM1/p62 to recruit LC3 and stimulate mitophagy
Sungwoo Park, Seon-Guk Choi, Seung-Min Yoo, Jin H Son & Yong-Keun Jung
Pages: 1906-1920
Published online: 30 Oct 2014
AbstractforCholine dehydrogenase interacts with SQSTM1/p62 to recruit LC3 and stimulate mitophagy | Full Text | References | PDF (1.6 MB) | Supplemental
  • 4262 Views
  • 92 CrossRef citations
  • 0Altmetric
Free Access
Article
Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions
Shane Deegan, Svetlana Saveljeva, Susan E Logue, Karolina Pakos-Zebrucka, Sanjeev Gupta, Peter Vandenabeele, Mathieu JM Bertrand & Afshin Samali
Pages: 1921-1936
Published online: 18 Dec 2014
AbstractforDeficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions | Full Text | References | PDF (1.4 MB) | Supplemental
  • 2986 Views
  • 42 CrossRef citations
  • 0Altmetric
Open Access
Article
Autophagy-dependent PELI3 degradation inhibits proinflammatory IL1B expression
Annika Klara Giegerich, Laura Kuchler, Lisa Katharina Sha, Tilo Knape, Heinrich Heide, Ilka Wittig, Christian Behrends, Bernhard Brüne & Andreas von Knethen
Pages: 1937-1952
Published online: 30 Oct 2014
AbstractforAutophagy-dependent PELI3 degradation inhibits proinflammatory IL1B expression | Full Text | References | PDF (1.3 MB) | Supplemental
  • 4610 Views
  • 52 CrossRef citations
  • 0Altmetric
Free Access
Article
The yeast autophagy protease Atg4 is regulated by thioredoxin
María Esther Pérez-Pérez, Mirko Zaffagnini, Christophe H Marchand, José L Crespo & Stéphane D Lemaire
Pages: 1953-1964
Published online: 30 Oct 2014
AbstractforThe yeast autophagy protease Atg4 is regulated by thioredoxin | Full Text | References | PDF (844.3 KB) | Supplemental
  • 2848 Views
  • 79 CrossRef citations
  • 0Altmetric
Free Access
Article
Autophagy in osteoblasts is involved in mineralization and bone homeostasis
Marie Nollet, Sabine Santucci-Darmanin, Véronique Breuil, Rasha Al-Sahlanee, Chantal Cros, Majlinda Topi, David Momier, Michel Samson, Sophie Pagnotta, Laurence Cailleteau, Séverine Battaglia, Delphine Farlay, Romain Dacquin, Nicolas Barois, Pierre Jurdic, Georges Boivin, Dominique Heymann, Frank Lafont, Shi Shou Lu, David W Dempster, Georges F Carle & Valérie Pierrefite-Carle
Pages: 1965-1977
Published online: 18 Dec 2014
AbstractforAutophagy in osteoblasts is involved in mineralization and bone homeostasis | Full Text | References | PDF (1.4 MB) | Supplemental
  • 7954 Views
  • 264 CrossRef citations
  • 0Altmetric
Free Access
Article
Acidocalcisome is required for autophagy in Trypanosoma brucei
Feng-Jun Li & Cynthia Y He
Pages: 1978-1988
Published online: 18 Dec 2014
AbstractforAcidocalcisome is required for autophagy in Trypanosoma brucei | Full Text | References | PDF (1.2 MB) | Supplemental
  • 1834 Views
  • 42 CrossRef citations
  • 0Altmetric
Free Access
Article
Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD
Sayak K Mitter, Chunjuan Song, Xiaoping Qi, Haoyu Mao, Haripriya Rao, Debra Akin, Alfred Lewin, Maria Grant, William Dunn Jr, Jindong Ding, Catherine Bowes Rickman & Michael Boulton
Pages: 1989-2005
Published online: 18 Dec 2014
AbstractforDysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD | Full Text | References | PDF (1.4 MB)
  • 8914 Views
  • 305 CrossRef citations
  • 0Altmetric
Free Access
Article
Inhibition of autophagy enhances the anticancer activity of silver nanoparticles
Jun Lin, Zhihai Huang, Hao Wu, Wei Zhou, Peipei Jin, Pengfei Wei, Yunjiao Zhang, Fang Zheng, Jiqian Zhang, Jing Xu, Yi Hu, Yanhong Wang, Yajuan Li, Ning Gu & Longping Wen
Pages: 2006-2020
Published online: 18 Dec 2014
AbstractforInhibition of autophagy enhances the anticancer activity of silver nanoparticles | Full Text | References | PDF (1.9 MB) | Supplemental
  • 6593 Views
  • 202 CrossRef citations
  • 0Altmetric
Free Access

Translational Research Papers

Article
A novel ATG4B antagonist inhibits autophagy and has a negative impact on osteosarcoma tumors
Debra Akin, S Keisin Wang, Pouran Habibzadegah-Tari, Brian Law, David Ostrov, Min Li, Xiao-Ming Yin, Jae-Sung Kim, Nicole Horenstein & William A Dunn Jr
Pages: 2021-2035
Published online: 30 Oct 2014
AbstractforA novel ATG4B antagonist inhibits autophagy and has a negative impact on osteosarcoma tumors | Full Text | References | PDF (1 MB) | Supplemental
  • 5293 Views
  • 170 CrossRef citations
  • 0Altmetric
Open Access
Article
Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity
Michelle Cicchini, Rumela Chakrabarti, Sameera Kongara, Sandy Price, Ritu Nahar, Fred Lozy, Hua Zhong, Alexei Vazquez, Yibin Kang & Vassiliki Karantza
Pages: 2036-2052
Published online: 30 Oct 2014
AbstractforAutophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity | Full Text | References | PDF (7.9 MB) | Supplemental
  • 7997 Views
  • 109 CrossRef citations
  • 0Altmetric
Open Access
Article
Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation
Daniela De Stefano, Valeria R Villella, Speranza Esposito, Antonella Tosco, Angela Sepe, Fabiola De Gregorio, Laura Salvadori, Rosa Grassia, Carlo A Leone, Giuseppe De Rosa, Maria C Maiuri, Massimo Pettoello-Mantovani, Stefano Guido, Anna Bossi, Anna Zolin, Andrea Venerando, Lorenzo A Pinna, Anil Mehta, Gianni Bona, Guido Kroemer, Luigi Maiuri & Valeria Raia
Pages: 2053-2074
Published online: 18 Dec 2014
AbstractforRestoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation | Full Text | References | PDF (1.5 MB) | Supplemental
  • 8539 Views
  • 125 CrossRef citations
  • 0Altmetric
Open Access

Autophagic Punctum

Article
Stationary phase lipophagy as a cellular mechanism to recycle sterols during quiescence
Chao-Wen Wang
Pages: 2075-2076
Published online: 18 Dec 2014
AbstractforStationary phase lipophagy as a cellular mechanism to recycle sterols during quiescence | Full Text | PDF (42.2 KB)
  • 1387 Views
  • 9 CrossRef citations
  • 0Altmetric
Free Access
Article
Using BRAFV600E as a marker of autophagy dependence in pediatric brain tumors
Jean M Mulcahy Levy, Nicholas K Foreman & Andrew Thorburn
Pages: 2077-2078
Published online: 18 Dec 2014
AbstractforUsing BRAFV600E as a marker of autophagy dependence in pediatric brain tumors | Full Text | PDF (45.1 KB)
  • 1188 Views
  • 16 CrossRef citations
  • 0Altmetric
Open Access
Article
MAPK8IP1/JIP1 regulates the trafficking of autophagosomes in neurons
Meng-meng Fu & Erika L F Holzbaur
Pages: 2079-2081
Published online: 30 Oct 2014
AbstractforMAPK8IP1/JIP1 regulates the trafficking of autophagosomes in neurons | Full Text | PDF (226.6 KB)
  • 1922 Views
  • 29 CrossRef citations
  • 0Altmetric
Free Access
Article Commentary
How to teach an old dog new tricks: Autophagy-independent action of chloroquine on the tumor vasculature
Hannelore Maes, Anna Kuchnio, Peter Carmeliet & Patrizia Agostinis
Pages: 2082-2084
Published online: 18 Dec 2014
AbstractforHow to teach an old dog new tricks: Autophagy-independent action of chloroquine on the tumor vasculature | Full Text | PDF (170.3 KB)
  • 1292 Views
  • 14 CrossRef citations
  • 0Altmetric
Free Access
Article
A role for TOR complex 2 signaling in promoting autophagy
Ariadne Vlahakis & Ted Powers
Pages: 2085-2086
Published online: 18 Dec 2014
AbstractforA role for TOR complex 2 signaling in promoting autophagy | Full Text | PDF (83.2 KB)
  • 1737 Views
  • 25 CrossRef citations
  • 0Altmetric
Free Access

Views and Commentaries

Article Commentary
Defining and measuring autophagosome flux—concept and reality
Ben Loos, André du Toit & Jan-Hendrik S Hofmeyr
Pages: 2087-2096
Published online: 18 Dec 2014
AbstractforDefining and measuring autophagosome flux—concept and reality | Full Text | References | PDF (640.5 KB) | Supplemental
  • 8350 Views
  • 185 CrossRef citations
  • 0Altmetric
Free Access

Explore articles

Explore the most recently published articles

GORASP2 promotes phagophore closure and autophagosome maturation into autolysosomes
Yusheng Xing et al.
Article | Published online: 26 Jul 2024
Spautin-1 promotes PINK1-PRKN-dependent mitophagy and improves associative learning capability in an alzheimer disease animal model
Juan Yi et al.
Article | Published online: 25 Jul 2024
Open Access
The emerging significance of Vac8, a multi-purpose armadillo-repeat protein in yeast
Hana Popelka et al.
Editorial | Published online: 24 Jul 2024
Free Access
FOXO-regulated DEAF1 controls muscle regeneration through autophagy
Kah Yong Goh et al.
Article | Published online: 20 Jul 2024
Open Access
View all latest articles