FCGR2C genotyping by pyrosequencing reveals linkage disequilibrium with FCGR3A V158F and FCGR2A H131R polymorphisms in a Caucasian population

Figures & data

Table 1. FCGR2C genotypes in a Caucasian population

Number of FCGR2C-ORF	Number of FCGR2C-STOP	Genotype^a
0	0	nul/nul	2
	1	STOP	21
	2	STOP/STOP	108
	3	STOP/STOP/STOP	20
Total			151 (79.9%)
1	0	ORF	0
	1	ORF/STOP	27
	2	ORF/STOP/STOP	1
	5	ORF/(STOP)5	1
2	0	ORF/ORF	6
	1	ORF/ORF/STOP	2
3	0	ORF/ORF/ORF	1
Total			38 (20.1%)

a Allele frequencies estimated from these genotypes are 12.6 and 87.4 respectively for FCGR2C-ORF and FCGR2C-STOP.

Figure 1.LD between FCGR2C-ORF/STOP, FCGR3A-V158F and FCGR2A-H131R. Polymorphisms of interest were localized on the genomic cluster using gene order and orientation annotated in build 37.2 of NCBI. For FCGR3A-V158F and FCGR2A-H131R, number of individual for each genotype is indicated depending on FCGR2C-ORF/STOP polymorphism.