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Emerging evidence of anti-tumor immune control in the central nervous system

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Pages 1648-1649 | Published online: 06 Dec 2012

Figures & data

Figure 1. Kaplan-Meier survival analysis demonstrating total immune cell infiltration in high-grade astrocytoma as an independent prognostic variable when combined with clinical performance score. High immune cell infiltration was defined as greater than median cytotoxic T cell, helper T cell or > 75th percentile microglia. Karnofsky/Lansky clinical performance score, was used to measure patient well-being. In this case, good performance was defined as greater than median. Cox proportional hazard multivariate analysis demonstrated that both high immune and good performance significantly contributed to longer survival (p values = 0.0077 and 0.0027, respectively).

Figure 1. Kaplan-Meier survival analysis demonstrating total immune cell infiltration in high-grade astrocytoma as an independent prognostic variable when combined with clinical performance score. High immune cell infiltration was defined as greater than median cytotoxic T cell, helper T cell or > 75th percentile microglia. Karnofsky/Lansky clinical performance score, was used to measure patient well-being. In this case, good performance was defined as greater than median. Cox proportional hazard multivariate analysis demonstrated that both high immune and good performance significantly contributed to longer survival (p values = 0.0077 and 0.0027, respectively).