Figures & data
Figure 1. Dynamic CTD phosphorylation patterns during the RNAP II transcription cycle. RNA Polymerase II (RNAP II) with hypophosphorylated CTD forms together with general transcription factors (GTFs) and the Mediator a preinitiation complex (PIC). During initiation, elongation and termination various CTD phosphorylation marks (P) are introduced and erased, successively. These CTD signatures determine the interaction capacity of RNAP II machinery for different transcription- and RNA processing factors (schematically presented by colored ovals).
