Figures & data
Figure 1. Hepcidin is primarily synthesized in hepatocytes and then released into the circulation. When hepcidin reaches circulation, it regulates iron metabolism by controlling iron transport to duodenal enterocytes and iron export from macrophages.
Figure 2. Schematic illustration of the crosstalk between the three main cell signaling pathways involved in the regulation of hepcidin and their modulation by HCV structural and non-structural proteins.
