Transcatheter embolization effectively controls acute lower gastrointestinal bleeding without localizing bleeding site prior to angiography

Abstract

Background and aims: Colonoscopy is preferred for treatment of lower gastrointestinal bleeding (LGIB). However, several conditions such as poor bowel preparation can cause endoscopic failure, leading to surgery or transcatheter therapy as alternative options. We aimed to assess the efficacy and safety of transcatheter arterial embolization (TAE) for LGIB in patients with endoscopic failure.

Methods: Between January 2005 and June 2015, 93 consecutive patients with acute LGIB underwent visceral angiography at three academic hospitals. Among them, a total of 52 patients were treated with TAE for LGIB and analyzed. Technical success, complications and 30-day rebleeding and mortality after TAE were investigated retrospectively in patients with and without localization of LGIB.

Results: Technical success of TAE was achieved in all patients. After TAE, 30-day rebleeding and mortality rate were 27% (14/52) and 29% (15/52), respectively. TAE was performed without localizing bleeding site in 32 of 52 patients (62%). Between patients with and without localized bleeding site, there were no significant differences in 30-day rebleeding rate (25% vs. 28%) and mortality rate (15% vs. 38%). Causes of death were mostly unrelated to bleeding. Only two cases of bowel infarction occurred after TAE in patients without bleeding site localization. Rebleeding could be predicted if the patient received more than six units of packed red blood cell transfusion before TAE in multivariate analysis.

Conclusions: TAE can be an effective treatment for LGIB even without localizing bleeding site.

Keywords:

• Angiography
• transcatheter arterial embolization
• lower gastrointestinal bleeding
• rebleeding
• mortality

Disclosure statement

All authors of this study have no conflict of interest to declare.

Additional information

Funding

This work was supported by the National Research Foundation of Korea (NRF) and grant funded by the Korean government (Ministry of Science, ICT & Future Planning) [NRF-2018M3A9E8021507, NRF-2017R1D1A1B03035104, NRF-2016R1C1B2015185 and NRF-2011-0031644].