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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 36, 2006 - Issue 6
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Original Articles

Synthesis and Fluorescence of N,N,N‐Trimethyl‐2‐[methyl(7‐nitrobenzo[c][l,2,5]oxadiazol‐4‐yl) amino]ethanaminium Iodide, a pH‐Insensitive Reporter of Organic Cation Transport

Bhasker Reddy Aavula Department of Chemistry, University of Arizona, Tucson, Arizona, USA
,
M. Ahad Ali Department of Chemistry, University of Arizona, Tucson, Arizona, USA
,
Eugene A. Mash Department of Chemistry, University of Arizona, Tucson, Arizona, USACorrespondence[email protected]
,
Dallas Bednarczyk Department of Physiology, University of Arizona, Tucson, Arizona, USA
&
Stephen H. Wright Department of Physiology, University of Arizona, Tucson, Arizona, USA
Pages 701-705 | Received 15 Sep 2005, Published online: 16 Aug 2006
 
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Abstract

A synthesis of the title compound, its characterization, and the pH dependence of its fluorescence properties are described. This compound serves as a pH‐insensitive real‐time reporter of organic cation transport in biological systems.

Acknowledgment

This research was supported in part by National Institutes of Health Awards DK49222, ES06694, and HL07249.

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