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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 44, 2014 - Issue 14
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Original Articles

Unified Approach to the Asymmetric Synthesis of Higher Homologues of (3-Quinolyl)-alanine

Shital K. Chattopadhyay Department of Chemistry, University of Kalyani, Kalyani, West Bengal, IndiaCorrespondence[email protected]
&
Indranil Kundu Department of Chemistry, University of Kalyani, Kalyani, West Bengal, India
Pages 2112-2120 | Received 04 Sep 2013, Published online: 09 Jun 2014
 
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Abstract

A new protocol based on a palladium-catalyzed Heck reaction of an amino acid–derived vinyl unit with 3-bromoquinoline has been developed to access the title compounds in good yield and optical purity.

GRAPHICAL ABSTRACT

ACKNOWLEDGMENT

This article is respectfully dedicated to the late Professor Alexander McKillop in admiration of his immense contribution to organic chemistry.

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