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Articles

Composite hydrogels based on gelatin, chitosan and polyvinyl alcohol to biomedical applications: a review

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Pages 1-20 | Received 10 Dec 2018, Accepted 09 Feb 2019, Published online: 05 Mar 2019
 

Abstract

Hydrogels produced from a single polymer show several disadvantages to biomedical applications. Binary and ternary blends of chitosan, gelatin, and polyvinyl alcohol can lead to hydrogels with better and desirable properties than those hydrogels made from a single polymer, which may be modulated on purpose. This article provides a brief overview of the advances in the fabrication of composite hydrogels using binary and ternary blends of gelatin, chitosan, and polyvinyl alcohol for biomedical applications, as well as different crosslinkers agents and crosslinking methods used to produce them. The availability of these materials will contribute to future biomaterials to biomedical applications.

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Disclosure statement

The authors declare no conflict of interest.

Additional information

Funding

This research was funded by “Fondo Sectorial de Investigación en Salud y Seguridad Social, SSA/IMSS/ISSSTE-CONACYT” grant number 234073. The authors would like to thank to CONACyT for the Ph.D. scholarship of M.Sc. Rogelio Rodríguez-Rodríguez and to Ean Hundley (Peace Corps/CIATEJ) for improving the English of the manuscript.

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