Recent advancements in hybridized polymer nano-biocomposites for tissue engineering

Abstract

Emerging novel approaches for bone tissue regeneration and engineering are based on bioactive materials scaffolding architectures for mimicking naturally occurring extracellular matrix while also acting as structural platform for cells attachment, multiplication, migration as well as functionalization. Polymeric nano-biocomposites formed from organic/inorganic hybrid biomaterials constructed from comingling of biodegradable polymeric matrices and bioactive inorganic substrates have recently garnered great attention as a result of prevalent efficient performances. Therefore, this paper expounds on state of the art recently emerging trends in bioactive, as well as biodegradable nanocomposites, along with organic/inorganic hybridized biomaterials, in addition to inherent usage for tissue engineering as well as bone regeneration. Emphases are given to nanocomposites oriented on bioactive glasses (BGs) and nanoparticulate hydroxyapatite (nHA)/polymeric matrices (PMs) along with their hybridized components.

Graphical Abstract

Keywords:

• Bioactive glass
• biomedical applications
• nanoparticles
• polymer nanocomposites

Acknowledgement

Vision-200 of Prof. Charles Esimone, Vice Chancellor, Nnamdi Azikiwe University, Awka, Nigeria is acknowledged. No funding is reported.

Disclosure statement

No potential conflict of interest was reported by the author(s).