The research status of biodegradable polymers in repair of Achilles tendon defects

Abstract

Achilles tendon defect is caused by direct or indirect violence that makes it difficult for the tensile strength of the Achilles tendon to resist external forces. It is characterized by a lack of tissue integrity around the Achilles tendon, local bruising or bacterial infection, and ultimately leads to abnormal gait. This paper reviews the recent research progress of biodegradable polymeric materials in treating Achilles tendon defects at home and abroad, mainly introducing the therapeutic impact on the repair of Achilles tendon defects from materials alone, materials combined with drugs or cells.

Graphical Abstract

Keywords:

• Achilles tendon defects
• biodegradable polymers
• drug delivery systems
• repair
• stem cells

Author contributions

Jinchi Zhang and Xiaolin Zhu wrote this article and equally contributed to this work; Peng Li and Siyun Chen revised this article; Jinzhe Zhang and Liqun Yang checked and review this article.

Disclosure statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Publisher’s note

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Additional information

Funding

This work was supported by the Natural Science Foundation of Liaoning Province [2022-YGJC-69], Shenyang Science and Technology Bureau [RC210239] and the support program for excellent young scholars of China Medical University.