ABSTRACT
We empirically demonstrate that graphical models can be a valuable tool in the identification of mediating variables in causal pathways. We make use of graphical models to elucidate the causal pathway through which the treatment influences the levels of fatigue and weakness in people living with HIV (PLHIV) based on a secondary analysis of a categorical dataset collected in a behavioral clinical trial: is weakness a mediator for the treatment and fatigue, or is fatigue a mediator for the treatment and weakness? Causal mediation analysis could not offer any definite answers to these questions.
Acknowledgments
The authors would like to thank the members of the International Nursing Network for HIV/AIDS Research for providing access to data used in this paper.
Disclosure statement
No potential conflict of interest was reported by the authors.
ORCID
Joachim G. Voss http://orcid.org/0000-0002-8072-6244