The cell culture of titanium alloy surface modifications by micro-powder blasting and co-blast techniques

ABSTRACT

The surface of Ti6Al4V substrate was modified by two ways: micro-powder blasting and co-blast technique. Micro-powder blasting was done using Al₂O₃ (of three different sizes) or SiC particles. Co-blast technique was done using the same particles co-blasted with hydroxyapatite (HA) particles. The morphology, roughness, deep impact and contact angle were used to characterise the surface modifications. The Ca/P atomic ratio was also determined by co-blast technique. Finally, the biocompatibility of Ti6Al4V substrate was investigated by surface modification in cell culture (osteoblast-like cell, MG63). The contact angle of Ti6Al4V substrate with surface modification is smaller than that without surface modification. The Ti6Al4V substrates by co-blast technique become more hydrophilic by co-blast technique and exhibit better cell proliferation.

KEYWORDS:

• Micro-powder blasting
• co-blast technique
• impact particle
• co-blasted particle
• physical–chemical properties
• cell culture

Disclosure statement

No potential conflict of interest was reported by the authors.

ORCID

Wei-Chiang Hung http://orcid.org/0000-0001-8543-3048