Advanced search
Publication Cover
Annals of Human Biology Volume 48, 2021 - Issue 1
Submit an article Journal homepage
90
Views
0
CrossRef citations to date
0
Altmetric
Human Biological Survey

Investigation of control region sequences of mtDNA in Naqu Tibetan population from Northwestern China

Wen-qing Yuea School of Fundamental Sciences, China Medical University, Shenyang, China
,
Mao-ling Suna School of Fundamental Sciences, China Medical University, Shenyang, China
,
Feng Hanb Medical Department, Shengjing Hospital affiliated to China Medical University, Shenyang, China
,
Jiu-jun Lic Department of Pediatrics, Shengjing Hospital affiliated to China Medical University, Shenyang, China;
,
Tsewang Rigzind Department of Internal Medicine, Naqu People's Hospital in Tibet, Naqu, China
,
Tashi Dhondupc Department of Pediatrics, Shengjing Hospital affiliated to China Medical University, Shenyang, China;;e Saijo Township Health Center, Naqu, China
,
Hai-bo Liua School of Fundamental Sciences, China Medical University, Shenyang, China
,
Dong-yue Lia School of Fundamental Sciences, China Medical University, Shenyang, China
,
Xuan Lif School of Innovation, China Medical University, Shenyang, China
,
Yan-ming Xuf School of Innovation, China Medical University, Shenyang, China
&
Xiao-na Lia School of Fundamental Sciences, China Medical University, Shenyang, ChinaCorrespondence[email protected]
 show all
Pages 70-77 | Received 28 May 2020, Accepted 17 Dec 2020, Published online: 22 Mar 2021
 
Sample our Health and Social Care journals, sign in here to start your FREE access for 14 days

Abstract

Background

The sequence polymorphisms of mitochondrial DNA (mtDNA) are valuable in forensic medicine and anthropological genetics.

Aim

We analysed the sequences of the mtDNA control region in 207 unrelated Tibetan individuals from the Naqu region, Tibet Autonomous Region in the People's Republic of China, and investigated the population structure of the region by population comparison with other groups.

Subjects and methods

Genomic DNA was extracted and hypervariable regions (HVS-I and HVS-II) were amplified and sequenced. Subsequently, sequences were aligned and compared with the revised Cambridge sequence. Moreover, population comparison was performed between the Naqu Tibetan group and the other groups.

Conclusion

Our study provided available data for exploring the mtDNA haplotype of the Tibetan population in the Naqu region, and population comparisons found that the Naqu Tibetan population has its own unique structure.

Disclosure statement

None of the authors have any interests to declare in relation to this submission.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later
PDF download + Online access
  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart
* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.