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Seminars in Ophthalmology Volume 37, 2022 - Issue 3
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Review

Aiding Adherence to Glaucoma Medications: A Systematic Review

Kristen L. Buehnea Department of Ophthalmology, Duke University School of Medicine, Durham, NC, USAORCID Iconhttps://orcid.org/0000-0002-4816-6216
, BSORCID Icon,
Jullia A. Rosdahla Department of Ophthalmology, Duke University School of Medicine, Durham, NC, USAORCID Iconhttps://orcid.org/0000-0002-0103-2077
, MD, PhDORCID Icon &
Kelly W. Muirb Durham Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, NC, USA;a Department of Ophthalmology, Duke University School of Medicine, Durham, NC, USACorrespondence[email protected]
, MD, MHS
Pages 313-323 | Received 21 Jun 2021, Accepted 27 Jul 2021, Published online: 17 Aug 2021
 
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ABSTRACT

Purpose

To provide a comprehensive assessment of the strategies studied to date that focus on improving glaucoma medication adherence.

Methods

A systematic review of the literature was conducted in MEDLINE (PubMed), Embase (Elsevier), and Scopus (Elsevier) from inception to March 1, 2021, of publications describing a device or strategy used to improve glaucoma medication adherence.

Results

42 studies described by 50 papers were included. Five categories were identified: reminder systems, medication simplifications, behavioral change programs, education, and alternative engagement strategies.

Conclusion

Most studies (40 of the 42) addressed the question of improved adherence directly, with 26 finding improved adherence. Notably, 14 examined the clinical effects of the intervention, either in terms of intraocular pressure (IOP) or visual fields. Only three found an improvement in IOP. None demonstrated a between group difference in visual field progression.

DISCLOSURE STATEMENT

The authors have no conflicts of interest to disclose.

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