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Case Report

EXTRANODAL TYPE T/NK-CELL LYMPHOMA WITH AN ATYPICAL CLINICAL PRESENTATION

, MD, , MD, , MD, , MD, , MD, , MD, , MD, , MD, , MD & , MD show all
Pages 291-299 | Received 20 Nov 2006, Accepted 16 Mar 2007, Published online: 09 Jul 2009
 

Abstract

Peripheral-type natural killer (NK)-or T-cell lymphomas are rare disorders characterized with clonal proliferation of mature lymphocytes. They have been linked to chronic and active Epstein-Barr virus infection (CAEBV), which itself is not defined as a malignant hematological disorder. The authors present a patient with T/NK-cell lymphoma involving skin, kidneys, spleen, pancreas, and meninges. She was remarkable for having the mosaic feature of more than one type of extranodal T/NK-cell lymphoma. She also had mixed findings of CAEBV that might have been attributed both to hypersensitivity to mosquito bites and to hemophagocytic lymphohistiocytosis.

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