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Case Report

SYNOVIAL SARCOMA OF THE NECK IN A CHILD: A Multidisciplinary Approach

, , , , , , , , & show all
Pages 431-437 | Received 08 Nov 2007, Accepted 18 Mar 2008, Published online: 09 Jul 2009
 

Abstract

Synovial sarcoma (SS) is the most common nonrhabdomyosarcomatous soft tissue sarcoma in childhood, but the head–neck site accounts for less than 5% of cases. The authors report a 10-year-old boy with SYT-SSX1 positive left parapharyngeal SS, resistant to front-line VAIA chemotherapy, who obtained a good partial response by salvage regimen (I3VE + CEV + I3VE) and local radiotherapy, so a complete surgical resection could be performed. The complete remission was subsequently consolidated by ablative high-dose chemotherapy, followed by autologous stem cell reinfusion. The child remains in complete remission at 36 months after completion of treatment.

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