Salt effect on bilayer phase transitions of dipalmitoylphosphatidylglycerol in saline water under high pressure

ABSTRACT

The phase transitions of dipalmitoylphosphatidylglycerol (DPPG) bilayer membrane at high NaCl concentrations under high pressure were investigated to construct the temperature–pressure phase diagram and to determine phase-transition properties. The constructed phase diagrams exhibited qualitative resemblance to that of the dipalmitoylphosphatidylcholine (DPPC) bilayer membrane: they showed the gel-phase polymorphism including the pressure-induced bilayer interdigitation. The phase-transition properties of the DPPG bilayer membrane changed in a salt concentration-dependent manner. We discussed the salt effect on the DPPG bilayer membrane from the variation in interactions between the polar head groups of the PG molecules.

KEYWORDS:

• Bilayer membrane
• dipalmitoylphosphatidylglycerol (DPPG)
• interdigitation
• phase transition
• Prodan fluorescence

Disclosure statement

The authors declare no conflict of interest.

ORCID

Masaki Goto http://orcid.org/0000-0003-0494-4212

Hitoshi Matsuki http://orcid.org/0000-0001-5061-405X