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Original Article

Prevalence and Risk Factors of Age-Related Macular Degeneration in South Korea: Korea National Health and Nutrition Examination Survey

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Received 10 May 2023, Accepted 18 Feb 2024, Published online: 20 Mar 2024
 

ABSTRACT

Purpose

To evaluate the prevalence and risk factors of age-related macular degeneration (AMD) in the Korean population.

Methods

In this cross-sectional study based on the Korea National Health and Nutrition Examination Survey (2017–2020) data 13,737 participants aged ≥ 40 years with assessable fundus images were included. The prevalence and risk factors of AMD were evaluated. The prevalence of early AMD, geographic atrophy (GA), and neovascular AMD were also assessed. Logistic regression analyses were used to identify risk factors.

Results

The prevalence (95% confidence interval [CI]) of AMD was 13.94% (13.15–14.72). The prevalence (95% CI) of early AMD, GA, and neovascular AMD was 13.07% (12.29–13.85), 0.26% (0.17–0.35), and 0.61% (0.47–0.75), respectively. The prevalence increased with age; it was 3.61%, 11.33%, 20.31%, 31.37%, and 33.98% in participants in their 40s, 50s, 60s, 70s, and ≥ 80 years, respectively. In multivariate analysis, AMD was positively associated with older age (p < 0.001; odds ratio [OR], 1.08; 95% CI, 1.07–1.09), male sex (p = 0.014; OR, 1.27; 95% CI, 1.05–1.53), and lower degree of education (p < 0.001; OR, 1.36 (for junior high school graduates); 95% CI, 1.12–1.65).

Conclusions

AMD was detected in approximately one-third of individuals aged ≥ 70 years, thus indicating that AMD is a common disease among older Koreans. Regular fundus examinations in populations with risk factors for AMD as well as education on methods to prevent or delay AMD progression, such as the Mediterranean diet, are necessary.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Supplementary material

Supplemental data for this article can be accessed online at https://doi.org/10.1080/09286586.2024.2321892.

Additional information

Funding

This study received support from the Kim’s Eye Hospital Research Fund.

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