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Comprehensive review

Meta-analysis of randomized controlled trials on calcium supplements and dairy products for changes in body weight and obesity indices

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, & ORCID Icon
Pages 615-631 | Received 06 Aug 2020, Accepted 24 Nov 2020, Published online: 08 Dec 2020
 

Abstract

This meta-analysis was performed to investigate whether calcium supplements and dairy products change obesity indices including fat mass. Original articles published in English between July 2009 and August 2019 were identified. Ten and 14 randomised controlled trials (RCTs) with ≥ 12 weeks interventions of calcium supplements and dairy products among overweight or obese adults aged ≥18 were critically reviewed. Mean difference (MD) or standardised mean difference (SMD) with 95% confidence interval (CI) were obtained using a random effect meta-analysis. Dairy products significantly changed fat mass (SMD, 95% CI; −0.40 [−0.77, −0.02]) and BMI (MD, 95% CI: −0.46 kg/m2 [−0.67, −0.26]), and calcium supplements also showed changes in fat mass (SMD, 95% CI; −0.15[−0.28, −0.02]). However, in the analysis of RCTs with low risk of bias scores, the significant changes remained only in the dairy-products intervention. Our findings suggest that dairy products without distinction of fat percentage may help reduce fat mass and BMI, but calcium supplements may not.

Disclosure statement

The authors declare that they have no conflicts of interest.

Author contributions

JY Hong was responsible for designing the review protocol, writing the protocol and report, conducting the search, screening potentially eligible studies, extracting and analysing data, interpreting results, updating reference lists, and creating tables. MK Kim was responsible for designing the review protocol and screening potentially eligible studies and contributed to writing the report, interpreting results, creating tables, and providing feedback on the report. HY Woo contributed to writing the report, arbitrating potentially eligible studies, extracting and analysing data, interpreting results, and providing feedback on the report. JS Lee contributed to screening potentially eligible studies and data extraction. AS Om and CK Kwock provided feedback on the report.

Additional information

Funding

This study was funded by the Korea Food Research Institute [E0150300-06].

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