The influence of yield surface shape and damage in the depth-dependent response of bone tissue to nanoindentation using spherical and Berkovich indenters

Abstract

Prevention and treatment of osteoporosis rely on understanding of the micromechanical behaviour of bone and its influence on fracture toughness and cell-mediated adaptation processes. Postyield properties may be assessed by nonlinear finite element simulations of nanoindentation using elastoplastic and damage models. This computational study aims at determining the influence of yield surface shape and damage on the depth-dependent response of bone to nanoindentation using spherical and conical tips. Yield surface shape and damage were shown to have a major impact on the indentation curves. Their influence on indentation modulus, hardness, their ratio as well as the elastic-to-total work ratio is well described by multilinear regressions for both tip shapes. For conical tips, indentation depth was not statistically significant (). For spherical tips, damage was not a significant parameter (). The gained knowledge can be used for developing an inverse method for identification of postelastic properties of bone from nanoindentation.

Keywords::

• bone
• nanoindentation
• parameter study
• yield surface shape
• damage

Acknowledgement

The authors would like to thank Dr Uwe Wolfram for his comments on the statistical analysis and for proofreading the manuscript.

Additional information

Funding

This work was supported by a Ph.D. scholarship of the German National Academic Foundation and the University of Bern.