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Research Articles

Iodine Mediated Oxidative Cross-Coupling of Benzo[d]Imidazo[2,1-b]Thiazoles with Ethylbenzene: An Unprecedented Approach of C3-Dicarbonylation

, , , , , & show all
Pages 4045-4054 | Received 14 Feb 2022, Accepted 14 May 2022, Published online: 02 Jun 2022
 

Abstract

A versatile approach of iodine mediated C3-dicarbonylation of benzo[d]imidazo[2,1-b]thiazoles (IBTs) with ethylbenzene has been reported. The reaction conditions were optimized by screening in various solvents, catalysts, and oxidants. The reaction is compatible with various substrates and was successfully demonstrated to offer moderate to good yields.

Graphical Abstract

Acknowledgements

The authors would like to thank Dr. Reddy’s Laboratory, Hyderabad for providing facilities to carry out this work.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

One of the authors Dr. Krishnaji, acknowledges CHRIST (Deemed to be University) for funding Major Research Project (MRP # MRPDSC-1723).

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