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Review Articles

Electrospray Ionization Ion Mobility Mass Spectrometry

ORCID Icon & ORCID Icon
Pages 483-497 | Published online: 22 Sep 2021
 

Abstract

Electrospray ionization ion mobility mass spectrometry (ESI-IMS—MS) is a rapidly progressing analytical technique for the examination of complex compounds in the gas phase. ESI-IMS—MS separates isomers, provides structural information, and quantitatively identifies peptides, lipids, carbohydrates, polymers, and metabolites in biological samples. ESI-IMS—MS has pharmaceutical, environmental, and manufacturing applications quickly characterizing drugs, petroleum products, and metal macromolecules. This review provides the history of ESI-IMS—MS development and applications to date.

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