A review of bacterial biofilm control by physical strategies

Abstract

Biofilms are multicellular communities of microorganisms held together by a self-produced extracellular matrix, which contribute to hygiene problems in the food and medical fields. Both spoilage and pathogenic bacteria that grow in the complex structure of biofilm are more resistant to harsh environmental conditions and conventional antimicrobial agents. Therefore, it is important to develop eco-friendly preventive methodologies to eliminate biofilms from foods and food contact equipment. The present paper gives an overview of the current physical methods for biofilm control and removal. Current physical strategies adopted for the anti-biofilm treatment mainly focused on use of ultrasound power, electric or magnetic field, plasma, and irradiation. Furthermore, the mechanisms of anti-biofilm action and application of different physical methods are discussed. Physical strategies make it possible to combat biofilm without the use of biocidal agents. The remarkable microbiocidal properties of physical strategies are promising tools for antimicrobial applications.

Keywords:

• Bacterial biofilm
• control
• electric
• physical method
• plasma
• ultrasound

Additional information

Funding

The research was supported by National Natural Science Foundation of China (21706037). The authors also gratefully acknowledge the financial support received from “One-Hundred Young Talents” scheme of Guangdong University of Technology (220413127).