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ABSTRACT
The volatile composition of the leaf, stem-bark, and nut of Artocarpus camansi (Moraceae) were studied. Essential oils were obtained by hydrodistillation in a modified Clevenger-type apparatus and analyzed by GC-MS. A total of 32, 11, and 26 compounds were identified, representing 99.09%, 99.45%, and 99.89% of the leaf, stem-bark, and nut oils, respectively. The main constituents of the leaf oil were m-xylene (36.82%), myristaldehyde (25.36%), phytol (6.21%), ethyl benzene(7.25%); those of the stem-bark were m-xylene (61.32%), o-xylene (18.76%), and ethyl benzene (16.21%); while the components of the nut oil were lanosteryl acetate (23.9%), olean-12-en-3y acetate (23.63%), 24-methylene cycloartenol (17.57%), m-xylene (15.26%), and squalene (2.85%). The leaf oils showed low activity against Shigella flexenari, Epidermic Methicilin-Resistant Staphylococcus aureus (EMRSA-17), Epidermic Methicilin-Resistant Staphylococcus aureus (EMRSA-16), drug-resistant clinical isolate of Pseudomonas aeruginosa (DRPA) and moderate activity against Samonella typhi. The stem-bark oil showed low activity toward P. aeruginosa and EMRSA-17 but was moderately active toward Escherichia coli and Salmonella typhi. The nut oil also showed low significant activity toward P. aeruginosa, EMRSA-17, and EMRSA-16, and was active toward E. coli, S. flexenari, S. typhi, and drug-resistant clinical isolate of P. aeruginosa.
Funding
The authors acknowledge The World Academy of Science (TWAS) for the award of the 2013 ICCBS-TWAS Sandwich Postgraduate Fellowship to Ms. Iniobong Ante with FR number: 3240275061 and H.E.J Research Institute of Chemistry, International Center for Chemical and Biological Sciences (ICCBS), University of Karachi, Pakistan, where the fellowship was held.