Abstract
Objective
This study aimed to investigate the changes in high-sensitivity C-reactive protein (hs-CRP) level and metabolic indices such as blood pressure, serum lipid level and serum glucose level according to grip strength in postmenopausal women.
Method
Data from participants (postmenopausal women) in the Seventh Korea National Health and Nutrition Examination Survey 2018 were analyzed. Absolute handgrip strength was the sum of the maximal grip strength of both hands, and relative handgrip was calculated as absolute handgrip divided by the body mass index. We performed linear regression analysis after adjusting for confounders to assess the influence of grip strength on hs-CRP level and metabolic indices.
Results
Linear regression analysis showed that after adjusting for confounders, with an increased absolute grip strength, systolic blood pressure and hs-CRP levels were decreased; however, the changes were not significant for the remaining indices. Relative grip strength was associated with hs-CRP levels and metabolic indices. With a high relative grip strength, hs-CRP, blood pressure, fasting blood glucose, hemoglobin A1c and triglyceride levels were decreased, while the high-density lipoprotein cholesterol level was increased.
Conclusion
Our study evaluated the overall health status using grip strength in postmenopausal women. The grip strength adjusted by body size was suitable in evaluating the overall health status, including inflammatory and metabolic indices. Additionally, increased grip strength was associated with a better health status in postmenopausal women.
摘要
目的:探讨绝经后女性根据握力变化对高敏C反应蛋白(hs-CRP)水平及血压、血脂、血糖等代谢指标的影响。
方法:对2018年第七次韩国国民健康营养调查的参与者(绝经后女性)的数据进行分析。绝对握力为双手最大握力之和, 相对握力为绝对握力除以身体质量指数。我们在调整混杂因素后进行线性回归分析, 以评估握力对hs-CRP水平和代谢指标的影响。
结果:线性回归分析显示, 校正混杂因素后, 绝对握力增加, 收缩压和hs-CRP水平降低;然而, 其余指标的变化并不明显。相对握力与hs-CRP水平和代谢指数相关。相对握力高时, hs-CRP、血压、空腹血糖、糖化血红蛋白、甘油三酯水平降低, 高密度脂蛋白胆固醇水平升高。
结论:我们的研究利用握力来评估绝经后妇女的整体健康状况。由体型调整的握力适合于评估整体健康状况, 包括炎症和代谢指标。此外, 握力的增加与绝经后妇女较好的健康状况相关。
Potential conflict of interest
The authors report no conflict of interest. The authors alone are responsible for the content and writing of the article.
Source of funding
Nil.