Surfactant and polymer layered carbon composite electrochemical sensor for the analysis of estriol with ciprofloxacin

ABSTRACT

This article exposes an approachable strategy for the responsive electrochemical analysis of estriol (ER) hormone by designing a sensitive and selective sensor of sodium dodecyl sulphate and polymerised xanthacridinum modified carbon nanotube and graphite composite paste electrode (SDS-PXAMCNTGCPE) via linear sweep voltammetry (LSV), cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. ER exposed a fine resolved irreversibly oxidised peak in phosphate buffer solution (PBS) of pH 7.0. CV and DPV reveal a commendable linear relation between oxidative peak current of ER and concentration of ER in the range 2 µM to 200 µM and 10 µM to 70 µM and they provide a promising lowest limit of detection (LOD) values of 2.9 × 10⁻⁷ M and 1.9 × 10⁻⁷ M. CV and DPV techniques were also applied to examine the selectivity of ER with Ciprofloxacin (CF). The adapting capability of SDS-PXAMCNTGCPE was accountable for the lower level identification of ER in sewage water as a real sample. The proposed sensor needs an easy preparation method with low cost and it exhibits superior sensitivity, stability, repeatability, and reproducibility.

Graphical Abstract

KEYWORDS:

• Estriol
• carbon composite sensor
• ciprofloxacin
• voltammetry
• xanthacridinum

Acknowledgments

We thankfully acknowledge the financial support from the Department of Science and Technology (DST), for the INSPIRE Fellowship (Registration number: IF180479), and VGST, Bangalore under the Research Project No. KSTePS/VGST - KFIST (L1)2016-2017/GRD-559/2017-18/126/333, 21/11/2017.

Disclosure statement

No potential conflict of interest was reported by the authors.

Correction Statement

This article has been republished with minor changes. These changes do not impact the academic content of the article.

Additional information

Funding

This work was supported by the VGST [KSTePS/VGST-KFIST (L1)2016-2017/GRD-559/2017-18/126/333, 21/11/2017].

Notes on contributors

Nagarajappa Hareesha

Nagarajappa Hareesha was born on 10th March 1994 in India. He is currently a PhD student under the guidance of Assistant professor Dr J. G. Manjunatha at Department of Chemistry, FMKMC College, A constituent College of Mangalore University, Madikeri, India. He received his Master degree in Chemistry from Davanagere University in 2017. His research interests are centered on development of the electrochemical sensors for the electrocatalytic investigation of biologically active molecules.

Jamballi G Manjunatha

Jamballi G Manjunatha was born on 25th February 1981 India. He is an Assistant professor in Chemistry, FMKMC College Madikeri (Mangalore University). He received his PhD degree in Chemistry from Kuvempu University in 2012 and Postdoc in Fellow from University of Kebangsaan Malaysia in 2014. His research interests focus on fabrication of electrochemical sensor for the detection of biologically active molecules and fabrication of binderlass supercapacitor.