190
Views
3
CrossRef citations to date
0
Altmetric
Research Article

Electrochemical investigation of allopurinol polymerised carbon paste electrode interface for epinephrine and folic acid sensing in pharmaceutical samples

, , , &
Pages 295-302 | Received 24 Jun 2021, Accepted 29 Aug 2021, Published online: 13 Sep 2021
 

ABSTRACT

The performance of simultaneous electro oxidation of epinephrine (EP) and folic acid (FA) was achieved at allopurinol polymerised carbon paste electrode (AlpM-CPE) by cyclic voltammetry (CV) method at physiological pH. The modified electrode showed remarkable sensing activity towards the electrooxidation of EP, involving irreversible 2-electronstransfer with adsorption-controlled kinetics. The results of varying few experimental parameters, for instance – scan rate, solution pH, concentration of the target analyte was examined. It was observed that, the anodic peak current (Ipa) is proportional to the concentration of EP in the range 51.02–318.18 μM with a calculated limit of detection (LOD) 0.46 µM by CV technique. The analytical applicability of the fabricated AlpM-CPE was examined for the resolve of EP in pharmaceutical sample and a good recovery results were observed.

5. Conflict of Interest

The authors declare no conflict of interest.

6. Credit author statement

A.B.T and P.S.G conceptualised the experimental idea and equally contributed. A.B.T, P.S.G and S.D.L performed the experiments. A.B.T and P.S.G took lead in the writing of the manuscript and equally contributed. S.N.D and B.E.K supervised the whole work. All authors agreed to the final version of the manuscript.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Log in via your institution

Log in to Taylor & Francis Online

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 286.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.