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Natural Product Research
Formerly Natural Product Letters
Volume 25, 2011 - Issue 13
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Short Communications

Major constituents and antimicrobial activity of Korean herb Acorus calamus

Wan-Jae Kim Department of Biotechnology, Bio-Food and Drug Research Center, College of Biomedical and Health Science, Konkuk University, Chungju 380-701, Korea
,
Keum-Hee Hwang Department of Biotechnology, Bio-Food and Drug Research Center, College of Biomedical and Health Science, Konkuk University, Chungju 380-701, Korea
,
Dong-Geun Park Department of Biotechnology, Bio-Food and Drug Research Center, College of Biomedical and Health Science, Konkuk University, Chungju 380-701, Korea
,
Tack-Joong Kim Division of Biological Science and Technology, Institute of Biomaterials, Yonsei University, Wonju 220-710, Korea
,
Dong-Woo Kim Natural F&P Co., Seoul 138-200, Korea
,
Dong-Kug Choi Department of Biotechnology, Bio-Food and Drug Research Center, College of Biomedical and Health Science, Konkuk University, Chungju 380-701, Korea
,
Won-Kook Moon Natural F&P Co., Seoul 138-200, Korea
&
Kwang-Ho Lee Department of Biotechnology, Bio-Food and Drug Research Center, College of Biomedical and Health Science, Konkuk University, Chungju 380-701, KoreaCorrespondence[email protected]
 show all
Pages 1278-1281 | Received 22 Dec 2009, Accepted 08 Jul 2010, Published online: 27 Jun 2011
 
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Abstract

The constituents and antimicrobial activity of the essential oil from Acorus calamus were analysed. Methyl isoeugenol and cyclohexanone were identified as the major constituents of the essential oil. The essential oil was tested for antimicrobial activity against bacteria and yeast, and has shown strong antibiotic activities against most of the tested microbes, except Escherichia coli. The hexane extract has shown a similar pattern of antimicrobial activity as the essential oil. Methyl isoeugenol, the most abundant constituent in the essential oil, has also shown similar antimicrobial activity, except against Bacillus subtilis. The essential oil as well as the hexane extract and methyl isoeugenol have shown antimicrobial activity against Propionibacterium acne, which is known to be involved in acne vulgaris.

Acknowledgement

This study was supported by the Konkuk University in 2009.

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