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Toxin Reviews Volume 36, 2017 - Issue 1
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Review Article

Advances in research of nephrotoxicity and toxic antagonism of ochratoxin A

Tao ZhaoDepartment of Food Quality and Safety, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, PR China,
,
Xiao Li ShenDepartment of Food Quality and Safety, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, PR China, Correspondence[email protected]
,
Wenying ChenDepartment of Food Quality and Safety, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, PR China,
,
Xin LiaoDepartment of Food Quality and Safety, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, PR China,
,
Jieyeqi YangDepartment of Food Quality and Safety, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, PR China,
,
Yan WangDepartment of Food Quality and Safety, Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing, PR China, and
,
Yan ZouDepartment of Food Quality and Safety, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, PR China,
&
Cuilan FangInspection & Testing Center, Chongqing Jiulongpo Municipal Center for Disease Control and Prevention, Chongqing, PR China
 show all
Pages 39-44 | Received 16 Aug 2016, Accepted 28 Sep 2016, Published online: 19 Oct 2016
 
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Abstract

Ochratoxin A (OTA) is a widespread mycotoxin that naturally takes place in various human foodstuffs, such as cereals, cereal products, fruits, vegetables, meat, eggs, dairy products, dried products, wine and even the infant formula. Thus, the generation of serious harm to human health is inevitable. Among a variety of toxicological effects of OTA, nephrotoxicity is the most prominent. Until present, the review focusing on the nephrotoxicity of OTA was absent. Therefore, the advances in research of nephrotoxicity, nephrotoxicity mechanisms and toxic antagonism of OTA were reviewed in the present paper.

Acknowledgements

The authors are grateful for the financial support from the District Program of National Natural Science Foundation of China (No. 31460426), the Youth Program of National Natural Science Foundation of China (No. 31601577), the cooperation projects of the Science and Technology Department of Guizhou Province (No. LH[2014]7546), the Beijing Natural Science Foundation (5154034), ZMKD2013-022, and cstc2014jcyjA00051.

Declaration of interest

All authors declare that there are no conflicts of interest.

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