225
Views
26
CrossRef citations to date
0
Altmetric
Review Article

Advances in research of nephrotoxicity and toxic antagonism of ochratoxin A

, , , , , , & show all
Pages 39-44 | Received 16 Aug 2016, Accepted 28 Sep 2016, Published online: 19 Oct 2016

References

  • Aydin S, Palabiyik SS, Erkekoglu P, et al. (2013). The carotenoid lycopene protects rats against DNA damage induced by Ochratoxin A. Toxicon 73:96–103
  • Baldi A, Losio MN, Cheli F, et al. (2004). Evaluation of the protective effects of alpha-tocopherol and retinol against ochratoxin A cytotoxicity. Br J Nutr 91:507–12
  • Boesch-Saadatmandi C, Loboda A, Jozkowicz A, et al. (2008). Effect of ochratoxin A on redox-regulated transcription factors, antioxidant enzymes and glutathione-S-transferase in cultured kidney tubulus cells. Food Chem Toxicol 46:2665–71
  • Boesch-Saadatmandi C, Wagner AE, Graeser AC, et al. (2009). Ochratoxin A impairs Nrf2-dependent gene expression in porcine kidney tubulus cells. J Anim Physiol Anim Nutr 93:547–54
  • Bondy GS, Caldwell DS, Aziz SA, et al. (2015). Effects of chronic ochratoxin A exposure on p53 heterozygous and p53 homozygous mice. Toxicol Pathol 43:715–29
  • Bui-Klimke TR, Wu F. (2015). Ochratoxin A and human health risk: a review of the evidence. Crit Rev Food Sci Nutr 55:1860–9
  • Chiusolo A, Defazio R, Casartelli A, et al. (2008). Regucalcin down-regulation in rat kidney tissue after treatment with nephrotoxicants. Toxicol Lett 182:84–90
  • Costa S, Utan A, Cervellati R, et al. (2007). Catechins: natural free-radical scavengers against ochratoxin A-induced cell damage in a pig kidney cell line (LLC-PK1). Food Chem Toxicol 45:1910–17
  • Dai Q, Zhao J, Qi X, et al. (2014). MicroRNA profiling of rats with ochratoxin A nephrotoxicity. BMC Genomics 15:333
  • Duarte SC, Pena A, Lino CM. (2010). A review on ochratoxin A occurrence and effects of processing of cereal and cereal derived food products. Food Microbiol 27:187–98
  • Gan F, Xue H, Huang Y, et al. (2015). Selenium alleviates porcine nephrotoxicity of ochratoxin A by improving selenoenzyme expression in vitro. PLoS One 10:e0119808
  • Hayakawa T, Matsuzawa A, Noguchi T, et al. (2006). The ASK1–MAP kinase pathways in immune and stress responses. Microbes Infect 8:1098–107
  • Hennemeier I, Humpf H-U, Gekle M, Schwerdt G. (2014). Role of microRNA-29b in the ochratoxin A-induced enhanced collagen formation in human kidney cells. Toxicology 324:116–22
  • Hong JT, Park KL, Han SY, et al. (2000). Effects of ochratoxin A on cytotoxicity and cell differentiation in cultured rat embryonic cells. J Toxicol Environ Health Part A 61:609–21
  • Huang Q, Dunn RT, Jayadev S, et al. (2001). Assessment of cisplatin-induced nephrotoxicity by microarray technology. Toxicol Sci 63:196–207
  • Kharasch ED, Schroeder JL, Bammler T, et al. (2006). Gene expression profiling of nephrotoxicity from the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (“Compound A”) in rats. Toxicol Sci 90:419–31
  • Klawitter J, Klawitter J, Schmitz V, et al. (2012). Low-salt diet and cyclosporine nephrotoxicity: changes in kidney cell metabolism. J Prot Res 11:5135–44
  • Kumar M, Dwivedi P, Sharma AK, et al. (2014). Apoptosis and lipid peroxidation in ochratoxin A- and citrinin-induced nephrotoxicity in rabbits. Toxicol Ind Health 30:90–8
  • Liang R, Shen XL, Zhang B, et al. (2015a). Apoptosis signal-regulating kinase 1 promotes ochratoxin A-induced renal cytotoxicity. Sci Rep 5:8078
  • Liang Z, Huang K, Luo Y. (2015b). Ochratoxin A and ochratoxin-producing fungi on cereal grain in China: a review. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 32:461–70
  • Limonciel A, Jennings P. (2014). A review of the evidence that ochratoxin A is an Nrf2 inhibitor: implications for nephrotoxicity and renal carcinogenicity. Toxins 6:371–9
  • Marin-Kuan M, Cavin C, Delatour T, Schilter B. (2008). Ochratoxin A carcinogenicity involves a complex network of epigenetic mechanisms. Toxicon 52:195–202
  • Marin-Kuan M, Nestler S, Verguet C, et al. (2006). A toxicogenomics approach to identify new plausible epigenetic mechanisms of ochratoxin A carcinogenicity in rat. Toxicol Sci 89:120–34
  • Marin DE, Taranu I. (2015). Ochratoxin A and its effects on immunity. Toxin Rev 34:11–20
  • Misawa H, Yamaguchi M. (2001). Involvement of nuclear factor-I (NF1) binding motif in the regucalcin gene expression of rat kidney cortex: the expression is suppressed by cisplatin administration. Mol Cell Biochem 219:29–37
  • Mor F, Kilic MA, Ozmen O, et al. (2014). The effects of orchidectomy on toxicological responses to dietary ochratoxin A in Wistar rats. Exp Toxicol Pathol 66:267–75
  • Morooka Y, Yamaguchi M. (2002). Suppressive effect of endogenous regucalcin on deoxyribonuclic acid synthesis in the nuclei of rat renal cortex. Mol Cell Biochem 229:157–62
  • Obrecht-Pflumio S, Grosse Y, Pfohlleszkowicz A, Dirheimer G. (1996). Protection by indomethacin and aspirin against genotoxicity of ochratoxin A, particularly in the urinary bladder and kidney. Arch Toxicol 70:244–8
  • Özcan Z, Gül G, Yaman I. (2015). Ochratoxin A activates opposing c-MET/PI3K/Akt and MAPK/ERK 1-2 pathways in human proximal tubule HK-2 cells. Arch Toxicol 89:1313–27
  • Palabiyik SS, Erkekoglu P, Zeybek ND, et al. (2013). Protective effect of lycopene against ochratoxin A induced renal oxidative stress and apoptosis in rats. Exp Toxicol Pathol 65:853–61
  • Patial V, Asrani RK, Patil RD, et al. (2013). Pathology of ochratoxin A-induced nephrotoxicity in Japanese quail and its protection by sea buckthorn (Hippophae rhamnoides L.). Avian Dis 57:767–79
  • Poór M, Kunsági-Máté S, Czibulya Z, et al. (2013). Fluorescence spectroscopic investigation of competitive interactions between ochratoxin A and 13 drug molecules for binding to human serum albumin. Luminescence 28:726–33
  • Qi X, Yang X, Chen S, et al. (2014a). Ochratoxin A induced early hepatotoxicity: new mechanistic insights from microRNA, mRNA and proteomic profiling studies. Sci Rep 4:5163
  • Qi X, Yu T, Zhu L, et al. (2014b). Ochratoxin A induces rat renal carcinogenicity with limited induction of oxidative stress responses. Toxicol Appl Pharmacol 280:543–9
  • Raghubeer S, Nagiah S, Phulukdaree A, Chuturgoon A. (2015). The phytoalexin resveratrol ameliorates ochratoxin A toxicity in human embryonic kidney (HEK293) cells. J Cell Biochem 116:2947–55
  • Raiola A, Tenore GC, Manyes L, et al. (2015). Risk analysis of main mycotoxins occurring in food for children: an overview. Food Chem Toxicol 84:169–80
  • Rouibah K, Houszka M, Dzimira S. (2013). Pathogenic effects of ochratoxin A. Medycyna Weterynaryjna 69:91–5
  • Schwartz GG. (2002). Hypothesis: does ochratoxin A cause testicular cancer? Cancer Causes Control 13:91–100
  • Shen XL, Zhang B, Liang R, et al. (2014). Central role of Nix in the autophagic response to ochratoxin A. Food Chem Toxicol 69:202–9
  • Shen XL, Zhang Y, Xu W, et al. (2013). An iTRAQ-based mitoproteomics approach for profiling the nephrotoxicity mechanisms of ochratoxin A in HEK 293 cells. J Proteom 78:398–415
  • Stachurska A, Ciesla M, Kozakowska M, et al. (2013). Cross-talk between microRNAs, nuclear factor E2-related factor 2, and heme oxygenase-1 in ochratoxin A-induced toxic effects in renal proximal tubular epithelial cells. Mol Nutr Food Res 57:504–15
  • Van Der Merwe KJ, S SP, Fourie L, et al. (1965). Ochratoxin A, a toxic metabolite produced by Aspergillus ochraceus Wilh. Nature 205:1112–13
  • Wilk-Zasadna I, Minta M. (2009). Developmental toxicity of ochratoxin A in rat embryo midbrain micromass cultures. Int J Mol Sci 10:37–49
  • Wu H-Z, Guo L, Mak Y-F, et al. (2011). Proteomics investigation on aristolochic acid nephropathy: a case study on rat kidney tissues. Anal Bioanal Chem 399:3431–9
  • Yamaguchi M. (2014). Regucalcin as a potential biomarker for metabolic and neuronal diseases. Mol Cell Biochem 391:157–66
  • Yamaguchi M. (2015). The potential role of regucalcin in kidney cell regulation: involvement in renal failure (review). Int J Mol Med 36:1191–9
  • Yang Q, He X, Li X, et al. (2014a). DNA damage and S phase arrest induced by Ochratoxin A in human embryonic kidney cells (HEK 293). Mutat Res 765:22–31
  • Yang Q, Shi L, Huang K, Xu W. (2014b). Protective effect of N-acetylcysteine against DNA damage and S-phase arrest induced by ochratoxin A in human embryonic kidney cells (HEK-293). Food Chem Toxicol 70:40–7
  • Zhang B, Shen XL, Liang R, et al. (2014). Protective role of the mitochondrial Lon protease 1 in ochratoxin A-induced cytotoxicity in HEK293 cells. J Proteom 101:154–68
  • Zingerle M, Silbernagl S, Gekle M. (1997). Reabsorption of the nephrotoxin ochratoxin A along the rat nephron in vivo. J Pharmacol Exp Ther 280:220–4
  • Zubiri I, Posada-Ayala M, Benito-Martin A, et al. (2015). Kidney tissue proteomics reveals regucalcin downregulation in response to diabetic nephropathy with reflection in urinary exosomes. Translat Res 166:474–84.e4

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.