Repeatability assessment of biometric measurements with different refractive states and age using a swept-source biometer

ABSTRACT

Background: We aim to assess if refractive error or age may influence the repeatability of measurements using a swept-source biometer.

Methods: A total of 61 subjects were evaluated with IOLMaster 700 acquiring measurements of axial length (AL), central corneal thickness (CCT), white-to-white distance (WTW), anterior aqueous depth (AQD), lens thickness (LT), and keratometry (K) readings. Repeatability was evaluated classifying the sample according to the refractive state and age by the calculation of the within-subject standard deviation (S_w), coefficient of repeatability, and intraclass correlation coefficient.

Results: Very similar S_w was acquired among groups for AL, CCT, and WTW. Differences found for AQD, LT, keratometry and astigmatism among refractive and age groups were not clinically significant. Refractive groups obtained a S_w for AQD between 0.016 and 0.026, while for LT was between 0.023 and 0.029 mm. Besides, S_w showed values from 0.014 to 0.029 mm for keratometry. Age groups obtained a S_w of 0.025 and 0.016 mm for AQD, and 0.029 and 0.018 mm for LT, respectively. S_w was 0.019 vs 0.018 mm for K1, 0.014 vs 0.031 mm for K2.

Conclusions: IOLMaster 700 showed good repeatability for biometric and keratometric parameters in eyes classified according to their refractive error or age.

KEYWORDS:

• Repeatability
• biometry
• anterior segment
• swept-source biometer
• refractive error
• age

Declaration of interest

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

Reviewer disclosures

Peer reviewers on this manuscript have no relevant financial or other relationships to disclose.

Authors contributions

N. Martínez-Albert: Conception and design of the study; Analysis and interpretation of the data; Paper drafting; Final approval of the last version. J. Esteve-Taboada: Conception and design of the study; Analysis and interpretation of the data; Critical revising; Final approval of the last version. R. Montés-Micó: Conception and design of the study; Paper drafting; Critical revising; Final approval of the last version. L. Fernández-Vega-Cueto: Analysis and interpretation of the data; Critical revising; Final approval of the last version. T. Ferrer-Blasco: Analysis and interpretation of the data; Critical revising; Final approval of the last version. All authors agree to be accountable for all aspects of the work.

Additional information

Funding

This paper was funded by the Grant Explora [SAF2013-49284-EXP] from  Spanish Ministry of Economy, Industry and Competitiveness, and by an ‘Atracció de Talent’ research scholarship [UV-INV-PREDOC16F1-385061] (University of Valencia) awarded to N Martínez-Albert.