Secondary Metabolites and their Biological Activities from Endophytic Fungal Strain Aspergillus terreus XJA8 Associated with Vernonia anthelmintica

Nigora Rustamova1 Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, South Beijing Road 40- Urumqi, Xinjiang830011, PRChina;2 State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi830011, PRChina;4 Department of Biology, Samarkand State University, University Boulevard 15, Samarkand703004, Uzbekistan

Khayrulla Bobakulov5 Institute of the Chemistry of Plant Substances, Academy of Sciences of Uzbekistan, Mirzo Ulugbek Str. 77, 100170Tashkent, Uzbekistan

Niu Litao1 Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, South Beijing Road 40- Urumqi, Xinjiang830011, PRChina;2 State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi830011, PRChina;3 University of Chinese Academy of Sciences, Beijing100039, PRChina

Rehebati Nuerxiati1 Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, South Beijing Road 40- Urumqi, Xinjiang830011, PRChina;2 State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi830011, PRChina

Ahmidin Wali1 Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, South Beijing Road 40- Urumqi, Xinjiang830011, PRChina;2 State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi830011, PRChina

William N. Setzer6 Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL35899, USA

Abulimiti Yili1 Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, South Beijing Road 40- Urumqi, Xinjiang830011, PRChina;2 State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi830011, PRChinaCorrespondence[email protected]

show all

Abstract

Two isocoumarins (6-methoxymellein and 6-hydroxymellein), one pyrrole compound (minaline), one lactone derivative (butyrolactone II), five phenolic acids (phenylacetic, veratric (3,4-dimethoxybenzoic), 4-hydroxyphenylacetic, 4-hydroxybenzoic and protocatechuic acid), and two phenolic acid methyl esters ((2-hydroxyphenyl) acetic acid methyl ester and methyl 4-hydroxyphenylacetate), along with 1,3-bis(4-hydroxyphenyl) propan-2-one were isolated from the fungal strain Aspergillus terreus XJA8. The fungal strain was isolated from the root of the medicinal plant Vernonia anthelmintica for first time. All isolated secondary metabolites were evaluated for their antimicrobial activity and melanin synthesis in murine B16 cells.

GRAPHICAL ABSTRACT

Keywords:

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Secondary Metabolites and their Biological Activities from Endophytic Fungal Strain Aspergillus terreus XJA8 Associated with Vernonia anthelmintica

Information for

Open access

Opportunities

Help and information

Secondary Metabolites and their Biological Activities from Endophytic Fungal Strain Aspergillus terreus XJA8 Associated with Vernonia anthelmintica

Abstract

GRAPHICAL ABSTRACT

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature