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Developmental Neuropsychology Volume 43, 2018 - Issue 1
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Systematic overview of neuroanatomical differences in ADHD: Definitive evidence

Bruno Bastos Vieira de MeloOccupational Therapy Department, Higher School of Health, Polytechnic Institute of Porto, Porto, Portugal;Faculty of Education Sciences, University of VigoCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-1543-6582
ORCID Icon,
Maria João TrigueiroOccupational Therapy Department, Higher School of Health, Polytechnic Institute of Porto, Porto, Portugal
&
Pedro Pereira RodriguesCINTESIS & Community Medicine, Information and Health Decision Sciences Department, Faculty of Medicine, University of Porto, Porto, Portugal
Pages 52-68 | Published online: 15 Dec 2017
 
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ABSTRACT

Objectives: This article seeks to identify neuroanatomical differences in ADHD through an overview of systematic reviews that report encephalic differences compared to a control group in volume, area, activation likelihood or chemical composition.

Methods: We conducted a systematic search using Cochrane guidelines and PRISMA criteria in PubMed, Scopus, Web of Science, Cochrane Database of Systematic Reviews and Database of Abstracts of Reviews of Effects.

Results: Results revealed broad encephalic involvement that includes a functional frontal and cingulate hypoactivation and structural differences in corpus callosum, cerebellum and basal nuclei.

Conclusions: ADHD symptoms might be due to a multi-network unbalanced functioning hypothesis.

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