Advanced search
Publication Cover
Expert Review of Proteomics Volume 2, 2005 - Issue 5
Submit an article Journal homepage
1,108
Views
204
CrossRef citations to date
0
Altmetric
Review

Histone structure and nucleosome stability

Leonardo Mariño-Ramírez National Institutes of Health, Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, Building 38A, Room 6S614M, 8600 Rockville Pike, Bethesda, MD 20894, USA. [email protected]
,
Maricel G Kann National Institutes of Health, Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, Building 38A, Room 8N811R, 8600 Rockville Pike, Bethesda, MD 20894, USA. [email protected]
,
Benjamin A Shoemaker National Institutes of Health, Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, Building 38A, Room 8N811Q, 8600 Rockville Pike, Bethesda, MD 20894, USA. [email protected]
&
David Landsman National Institutes of Health, Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, Building 38A, Room 6N601, 8600 Rockville Pike, MSC 6075, Bethesda, MD 20894-6075, USA. [email protected]
Pages 719-729 | Published online: 09 Jan 2014
 
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

Abstract

Histone proteins play essential structural and functional roles in the transition between active and inactive chromatin states. Although histones have a high degree of conservation due to constraints to maintain the overall structure of the nucleosomal octameric core, variants have evolved to assume diverse roles in gene regulation and epigenetic silencing. Histone variants, post-translational modifications and interactions with chromatin remodeling complexes influence DNA replication, transcription, repair and recombination. The authors review recent findings on the structure of chromatin that confirm previous interparticle interactions observed in crystal structures.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 99.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 641.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.