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Review

The enigma of sleep

Pages 245-254 | Received 21 Jul 2016, Accepted 20 Sep 2016, Published online: 21 Oct 2016
 

Abstract

Sleep has a critical role in promoting and maintaining neurological health and organismal homeostasis. Research over the past 135 years has brought significant understanding on various aspects of sleep biology; however, many questions still remain around the role and function of sleep. Sleep clearly has a powerful influence on infectious disease, cardiovascular health and neurological disorders. During the modern age, the majority of investigation into sleep has focused on identifying the biological factors underlying the effect of sleep on various pathological conditions. Disorders of sleep have the power to affect neuroimmunity, cognition and the development of neurological disorders such as Alzheimer's and autism. This present short review will highlight these factors affecting sleep.

Financial & competing interests disclosure

The author has no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.

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