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Abstract
Acquired immunodeficiency syndrome (AIDS) is an increasing problem in the pediatric population. Beta-2-microglobulin is part of the HLA structure, being especially abundant in the lymphoid celis and the most useful nonspecific indicium of AIDS. Serum beta-2-microglobulin assayed in 271 healthy children had a geometric mean of 1.398 mg/L and a 5–95 percentile interval of 0.925–2.202 mg/L; thus, values above 2.202 mg/L may be indicative of active disease.